Monitored panel
Every variant this workspace tracks, with the interpretation on record beside the interpretation held today.
Classification drift
The interpretation moved across the clinically actionable boundary since this result was reported.
Evidence strengthened
The interpretation moved further toward pathogenicity without crossing a band boundary.
Evidence weakened
Accumulated evidence now favours a more benign interpretation than the one reported.
Consensus conflict
Submitters no longer agree on how this variant should be classified.
Regional conflict
Regional evidence reaches a different conclusion from the global consensus.
No material change
Current evidence agrees with the interpretation on record.